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CAS NO.12629-01-5
99(1-2)Kilogram
human growth hormone Hgh 191AA factory 12629-01-5 in bulk supply 12629-01-5 trader
Somatotropin, a second-generation (methionine-free) human growth hormone produced by recombinant technology, was launched in the U.S.A. for the treatment of growth failure in children due to chronic renal insufficiency before transplantation and for the long term treatment of short stature in children with growth failure due to a lack of endogenous growth hormone secretion. The efficacy of somatotropin is reportedly comparable to the first biosynthetic growth hormone somatrem, which contains a methionyl residue, but with less frequent antibody formation and rarely causes allergic effects or impairs growth response. Somatotropin is also in clinical trials for the treatment of growth hormone deficiency in adults and is currently under approval review for Turner's syndrome.
Human growth hormone (hGH, alternative name: somatotropin) is a polypeptide with 191 amino acid residues and a molecular weight of about 22kDa. It is known as a therapeutic drug for hypophyseal dwarfism because it promotes the growth of tissues and organs in vivo through the production of insulin-like growth factor (alternate name: somatomedin). In vitro, it was found to act directly on cells and promote their proliferation, indicating a very useful tool as a research reagent.
This product is des-phe somatotropin.
Pronounce:
Somatropin
Other Names:
Genotropin, Humatrope, Nutropin AQ NuSpin, Nutropin, Norditropin FlexPro, Omnitrope, Saizen, Zomacton (brand products for the treatment of growth disorders and growth hormone deficiency); Zorbtive (brand product for the treatment of short bowel syndrome); Serostim (brand product for the treatment of HIV wasting or cachexia); r-hGH, recombinant hGH, recombinant human GH, recombinant human growth hormone, somatotropin
Drug Class:
Immune Modulators
Molecular Formula:
C990H1528 N262 O300 S7
Registry Number:
12629-01-5 (CAS)
Chemical Name:
Growth hormone (human)
Chemical Class:
Carboxylic acids and derivatives
Phase of Development:
Somatropin is in Phase 2 development as an immune modulator for the treatment of HIV infection.
FDA-Approved Product for HIV-Related Treatment: Somatropin is FDA-approved under the brand name Serostim for the treatment of HIV-associated wasting or cachexia.