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CAS NO.501-30-4
Kojic acid manufacturer 501-30-4 in stock low price 501-30-4
kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating.
Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase.It decreases growth of Leishmania parasites in vitro and in vivo, and it protects mice from damage induced by gamma irradiation. Kojic acid has been used as a food additive to prevent enzymatic browning. Formulations containing kojic acid are used in the treatment of hyperpigmentation disorders
Kojic acid may be used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors and in cosmetics to lighten skin. It is used to treat skin diseases like melasma as it has antibacterial and antifungal properties. It is used as a chelation agent that inhibits melanin production and also as a tyrosine kinase inhibitor.
Kojic acid is a tyrosinase inhibitor that acts as a chelation agent which inhibits melanin production which in vitro should help melasma. It can be used on chemicals to prevent oxidative browning of samples.
| Catalogue Number | K655080 |
| Chemical Name | Kojic Acid |
| Synonyms | 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one; 5-Hydroxy-2-hydroxymethyl-4-pyrone; 5-Hydroxy-2-(hydroxymethyl)-4H-pyranone; 2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one; NSC 1942; |
| CAS Number | 501-30-4 |
| Molecular Formula | C?H?O? |
| Appearance | Off-White to Beige Solid |
| Melting Point | >150°C (dec.) |
| Molecular Weight | 142.11 |
| Storage | Refrigerator |
| Solubility | DMSO, Methanol (Slightly) |
| Category | Building Blocks; Miscellaneous; |
| Applications | A naturally occurring chelation agent. |