Welcome to LookChem.com Sign In|Join Free

shanghai Longyu biotechnology Co.,Ltd

Free supplier Enterprise Certification

Free
supplier
4th
years
Home>>Products>>Ibutamoren Mesylate(MK677) in bulk supply 159752-10-0 global trade Hot Sale 159752-10-0

Products Categories

Product Certification&
Enterprise Certification

More Detail

shanghai Longyu biotechnology Co.,Ltd

Country: China (Mainland)

Business Type:Lab/Research institutions

Ms.Monica

Tel: 86-15821988213

Mobile: 86-15821988213

Tel: 86-15821988213

Fax:

URL: http://www.longyupharma.com

Province/state: Shanghai

City: Shanghai

Street: Dalian Rd 950th

MaxCard:


Contact Suppliers

Ibutamoren Mesylate(MK677) in bulk supply 159752-10-0 global trade Hot Sale 159752-10-0

CAS NO.159752-10-0

  • Min.Order: 0 Metric Ton
  • Payment Terms:
Contact Supplier

Product Details

Keywords

  • Ibutamoren Mesylate(MK677) in bulk supply
  • 159752-10-0 global trade
  • Hot Sale 159752-10-0

Quick Details

  • ProName: Ibutamoren Mesylate(MK677) in bulk sup...
  • CasNo: 159752-10-0
  • Molecular Formula: C27H36N4O5S.CH4O3S
  • Appearance: White solid
  • Application: pharmaceutical intermediates
  • DeliveryTime: 1 week
  • PackAge: 1kg/Aluminum foil package, 25Kg/Drum
  • Port: Shenzhen,Qingdao,Guangzhou
  • ProductionCapacity: Metric Ton/Day
  • Purity: >99%
  • Storage: Normal temperature
  • Transportation: FEDEX,DHL,EMS,Special line guarantee d...
  • LimitNum: 0 Metric Ton
  • Moisture Content: 1226
  • Impurity: 0

Superiority

Ibutamoren Mesylate(MK677) in bulk supply 159752-10-0 global trade Hot Sale 159752-10-0

Ibutamoren, also known as MK-677 or L-163,191, is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.

Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue receptor (GHSR). Ibutamoren is an orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue. It elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of aldosterone, luteinizing hormone, thyroxine, or prolactin

Details

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Ibutamoren, also known as MK-677, MK-0667, and L-163,191, is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels.

Hot Product