Keywords

• Nicotinamide riboside chloride Wholesaler
• 23111-00-4 factory supply
• 23111-00-4 supplier

Quick Details

• ProName: Nicotinamide riboside chloride Wholesa...
• CasNo: 23111-00-4
• Molecular Formula: C11H15N2O5.Cl
• Appearance: White solid
• Application: pharmaceutical intermediates
• DeliveryTime: 1 week
• PackAge: 1kg/Aluminum foil package, 25Kg/Drum
• Port: Shenzhen,Qingdao,Guangzhou
• ProductionCapacity: Metric Ton/Day
• Purity: >99%
• Storage: Normal temperature
• Transportation: FEDEX,DHL,EMS,Special line guarantee d...
• LimitNum: 0 Metric Ton
• Moisture Content: 1013
• Impurity: 0

Superiority

Nicotinamide riboside chloride Wholesaler 23111-00-4 factory supply 23111-00-4 supplier

Nicotinamide riboside, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. NR blocks degeneration of surgically severed dorsal root ganglion neurons ex vivo and protects against noise-induced hearing loss in living mice. Nicotinamide riboside prevents muscle, neural and melanocyte stem cell senescence. Increased muscular regeneration in mice has been observed after treatment with nicotinamide riboside, leading to speculation that it might improve regeneration of organs such as the liver, kidney, and heart. Nicotinamide riboside also lowers blood glucose and fatty liver in prediabetic and type 2 diabetic models while preventing the development of diabetic peripheral neuropathy. Note: Nicotinamide Riboside chloride is a α/β mixture

Nicotinamide Riboside is an NAD⁺ precursor. It is a substrate for nicotinamide riboside kinases (NRK1/2). Nicotinamide Riboside shows neuroprotective effects in a mouse model of type 2 diabetes and improves mitochondrial function in muscle stem cells in aged mice. The compound also corrects non-alchoholic fatty liver disease phenotype induced by NAD⁺ deficiency or high-fat diet in mice. 

Nicotinamide Riboside Chloride (NIAGEN) is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD⁺ .NIAGEN is generally recognized as safe (GRAS) in the United States for use in food products. Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements.

Details

CAS Number

23111-00-4

Name

Nicotinamide riboside chloride NR-CL

Synonyms

3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride [ACD/IUPAC Name]
23111-00-4 [RN]
3-Carbamoyl-1-(β-D-ribofuranosyl)pyridiniumchlorid [German] [ACD/IUPAC Name]
8XM2XT8VWI
Chlorure de 3-carbamoyl-1-(β-D-ribofuranosyl)pyridinium [French] [ACD/IUPAC Name]
Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1) [ACD/Index Name]
1-ribosylnicotinamide chloride
3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride
MFCD27952781
Nicotinamide B-D Riboside Chloride(WX900111)
Nicotinamide Riboside Chloride
Nicotinamide-β-D-riboside chloride

SMILES

c1cc(c[n+](c1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N.[Cl-]

StdInChI

InChI=1S/C11H14N2O5.ClH/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11;/h1-4,7-9,11,14-16H,5H2,(H-,12,17);1H/t7-,8-,9-,11-;/m1./s1

StdInChIKey

YABIFCKURFRPPO-IVOJBTPCSA-N

Molecular Formula

C₁₁H₁₅ClN₂O₅

Molecular Weight

290.7

MDL Number

MFCD27952781

Properties

Appearance

White powder