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shanghai Longyu biotechnology Co.,Ltd

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best quality Melatonin 73-31-4 reasonable price High Purity 73-31-4

CAS NO.73-31-4

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Keywords

  • best quality Melatonin
  • 73-31-4 reasonable price
  • High Purity 73-31-4

Quick Details

  • ProName: best quality Melatonin 73-31-4 reasona...
  • CasNo: 73-31-4
  • Molecular Formula: C13H16N2O2
  • Appearance: White solid
  • Application: pharmaceutical intermediates
  • DeliveryTime: 1 week
  • PackAge: 1kg/Aluminum foil package, 25Kg/Drum
  • Port: Shenzhen,Qingdao,Guangzhou
  • ProductionCapacity: Metric Ton/Day
  • Purity: >99%
  • Storage: Normal temperature
  • Transportation: FEDEX,DHL,EMS,Special line guarantee d...
  • LimitNum: 0 Metric Ton
  • Moisture Content: <0.728
  • Impurity: 0

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best quality Melatonin 73-31-4 reasonable price High Purity 73-31-4

Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity - antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

Melatonin is an indoleamine neurohormone whose levels vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions in animals, plants, and microbes. Many biological effects of melatonin are transduced through melatonin receptors, including the MT1, MT2, and MT3 subtypes. Melatonin also acts as a powerful antioxidant that protects lipids, proteins, and DNA against oxidative damage. Glutathione peroxidase, superoxide dismutases, and catalase are upregulated by melatonin, and melatonin scavenges free radicals as a terminal antioxidant.

Melatonin is an endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.

Details

Melatonin acts as a neurohormone that upregulates antioxidant enzymes and inhibits rat NOS1. It also acts as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

Alternate Name N-Acetyl-5-methoxytryptamine; NSC 113928; Regulin; NSC 56423
Appearance White solid
CAS # 73-31-4
Molecular Formula C??H??N?O?
Molecular Weight 232.28
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
SMILES CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
InChi InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
InChi Key DRLFMBDRBRZALE-UHFFFAOYSA-N
PubChem CID 896
MDL Number MFCD00005655
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.
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