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shanghai Longyu biotechnology Co.,Ltd

Country: China (Mainland)

Business Type:Lab/Research institutions

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Tel: 86-15821988213

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best quality Azithromycin reasonable price 83905-01-5 High Purity 83905-01-5

CAS NO.83905-01-5

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  • best quality Azithromycin
  • reasonable price 83905-01-5
  • High Purity 83905-01-5

Quick Details

  • ProName: best quality Azithromycin reasonable p...
  • CasNo: 83905-01-5
  • Appearance: White solid
  • Application: pharmaceutical intermediates
  • DeliveryTime: 1 week
  • PackAge: 1kg/Aluminum foil package, 25Kg/Drum
  • Port: Shenzhen,Qingdao,Guangzhou
  • ProductionCapacity: Metric Ton/Day
  • Purity: >99%
  • Storage: Normal temperature
  • Transportation: FEDEX,DHL,EMS,Special line guarantee d...
  • LimitNum: 0 Metric Ton

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best quality Azithromycin reasonable price High Purity 83905-01-5

Macrolide antibiotic, 15-membered nitrogen-containing heterocyclic, antibacterial mechanism is similar to Erythromycin, but antibacterial spectrum is broader. The antibacterial activity of Gram-positive bacteria is stronger. As for Gram-negative bacteria such as Haemophilus influenzae, Salmonella, E. coli, Shigella bacteria, it have strong antibacterial activity. And it is acid stable and well tolerated. It has a very good therapeutic effect on respiratory tract infections, skin and soft tissue infections, sexually transmitted diseases which are caused by sensitive bacteria.

Oral administration
1. Community-acquired pneumonia: intravenous infusion for at least 2 days turning into oral administration, once 500 mg, 1 times a day, 7-10 day for a course.
2. For sexually transmitted diseases caused by Chlamydia trachomatis, Duke Haemophilus or sensitive Neisseria gonorrhoeae, only a single oral dose of 1g.
3. Pelvic inflammation disease: intravenous infusion for 1-2 days turning into oral administration, once 250 mg, 1 time a day, 7 day a course of treatment.
Intravenous infusion
1.Community-acquired pneumonia: one 500mg, once a day, at least continuous medication for 2 days, followed by turning into oral administration. Usage and dosage see oral administration items.
2. Pelvic inflammatory disease: an adult once 500 mg, 1 times a day, 1-2 days of medication, using the drug for oral administration. Usage and dosage see oral administration items.
Renal insufficiency dose
Patients with mild renal insufficiency (creatinine clearance rate is greater than 40ml/min) are no need for dose adjustment.
Hepatic insufficiency dose
Patients with mild to moderate hepatic dysfunction are no need for dose adjustment.
Elderly dosage: Usage and dosage is same as adults.

Details

Azithromycin is an azalide antibiotic, which inhibits the growth of gram negative bacteria, such as Haemophilus influenza. Azithromycin functions by interfering with 50S ribosomal subunit formation and translation, which inhibits the formation of proteins essential for bacterial survival. Studies involving capillary electrophoresis suggest that Azithromycin can be used as a chiral selector for enantiomeric separation of compounds. In addition, Azithrmycin can be used to increase chloride efflux and selectively reduces tumor necrosis factor α in human cystic fibrosis cells. Furthermore, Azithromycin reduces LPS-induced pulmonary neutrophilia in mice, via suppressing the expression of IL-1β.

 

Alternate Name 13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
Appearance White solid
CAS # 83905-01-5
Molecular Formula C??H??N?O??
Molecular Weight 748.98
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
InChi CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
InChi Key MQTOSJVFKKJCRP-BICOPXKESA-N
PubChem CID 447043
MDL Number MFCD00873574
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.
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